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Yuek Ling Chai Selected Research

Dementia (Dementias)

12/2021Low plasma ergothioneine levels are associated with neurodegeneration and cerebrovascular disease in dementia.
1/2019Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration.
11/2017An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias.
1/2017Increased Transforming Growth Factor β2 in the Neocortex of Alzheimer's Disease and Dementia with Lewy Bodies is Correlated with Disease Severity and Soluble Aβ42 Load.
8/2016Growth differentiation factor-15 and white matter hyperintensities in cognitive impairment and dementia.
1/2016Apolipoprotein ɛ4 is Associated with Dementia and Cognitive Impairment Predominantly Due to Alzheimer's Disease and Not with Vascular Cognitive Impairment: A Singapore-Based Cohort.
1/2015Markers of cardiac dysfunction in cognitive impairment and dementia.

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Yuek Ling Chai Research Topics

Disease

8Alzheimer Disease (Alzheimer's Disease)
01/2021 - 01/2014
7Dementia (Dementias)
12/2021 - 01/2015
6Cognitive Dysfunction
12/2021 - 01/2015
5Cerebrovascular Disorders (Cerebrovascular Occlusion)
12/2021 - 01/2015
3Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy)
01/2020 - 01/2014
2Vascular Diseases (Vascular Disease)
12/2021 - 01/2021
1Astrocytoma (Pilocytic Astrocytoma)
01/2020
1Neuroinflammatory Diseases
01/2020
1Inflammation (Inflammations)
01/2020
1Siderosis
01/2019
1Lewy Body Disease (Lewy Body Dementia)
01/2019
1Cerebral Hemorrhage
01/2019
1Cerebral Amyloid Angiopathy (Congophilic Angiopathy)
01/2019
1Stroke (Strokes)
01/2019
1Parkinson Disease (Parkinson's Disease)
01/2017
1Amyloid Plaque
01/2017
1Heart Diseases (Heart Disease)
01/2017
1Cardiovascular Diseases (Cardiovascular Disease)
08/2016
1Guillain-Barre Syndrome
01/2014

Drug/Important Bio-Agent (IBA)

8Biomarkers (Surrogate Marker)IBA
12/2021 - 01/2014
2CytokinesIBA
01/2021 - 01/2020
2Apolipoproteins E (ApoE)IBA
01/2019 - 01/2016
2SynucleinsIBA
01/2019 - 01/2017
2Amyloid (Amyloid Fibrils)IBA
11/2017 - 01/2017
1hercynineIBA
12/2021
1AntioxidantsIBA
12/2021
1ErgothioneineIBA
12/2021
1ThionesIBA
12/2021
1OsteopontinIBA
01/2021
1LipidsIBA
01/2020
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
01/2020
1Cathepsin DIBA
01/2019
1ProteomeIBA
11/2017
1Proteins (Proteins, Gene)FDA Link
11/2017
1Protein Isoforms (Isoforms)IBA
01/2017
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2017
1Interleukin-8 (Interleukin 8)IBA
01/2017
1Growth Differentiation Factor 15IBA
08/2016
1ApolipoproteinsIBA
01/2016
1Apolipoprotein E4IBA
01/2016
1Troponin T (Troponin T1)IBA
01/2015
1pro-brain natriuretic peptide (1-76)IBA
01/2015
1ImmunosorbentsIBA
01/2014
1AntibodiesIBA
01/2014
1Immunoglobulin M (IgM)IBA
01/2014
1EnzymesIBA
01/2014
1Immunoglobulin G (IgG)IBA
01/2014
1GangliosidesIBA
01/2014
1AutoantibodiesIBA
01/2014

Therapy/Procedure

1Immunomodulation
01/2020